Genetics of alcoholic liver disease and non-alcoholic steatohepatitis
نویسندگان
چکیده
منابع مشابه
[Non-alcoholic fatty liver disease and non-alcoholic steatohepatitis].
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are the hepatic manifestations of the metabolic syndrome. Since the prevalence of obesity and consequently of the metabolic syndrome is steadily increasing, the different types of NAFLD are nowadays the most common cause of liver injury in North America. The development of NASH and fatty liver cirrhosis occurs af...
متن کاملCurrent solutions for obesity-related liver disorders: non-alcoholic fatty liver disease and non-alcoholic steatohepatitis.
o besity is a worldwide epidemic with more than 1 billion overweight adults and at least 300 million obese patients [1]. According to recent statistics from the United States, 16.9% of children and adolescents aged 2–19 years were obese in 2009–2010 and 31.8% were either overweight or obese [2]. The rise in childhood obesity has been accompanied by an increase in pediatric liver diseases: 70%–8...
متن کاملSystematic review: the diagnosis and staging of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis
BACKGROUND Non-alcoholic fatty liver disease (NAFLD) has become the most prevalent cause of liver disease in Western countries. The development of non-alcoholic steatohepatitis (NASH) and fibrosis identifies an at-risk group with increased risk of cardiovascular and liver-related deaths. The identification and management of this at-risk group remains a clinical challenge. AIM To perform a sys...
متن کاملSurgical treatment of non-alcoholic steatohepatitis and non-alcoholic fatty liver disease.
BACKGROUND Overweight and obesity are the most significant risk factors for the development of hepatic steatosis, non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD) in children and adults. Both have been increasingly implicated in the genesis of hepatic fibrosis and cirrhosis. However, no consensus exists about whether weight reduction may reverse this process. ...
متن کاملAn Animal Model for the Juvenile Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis
Non Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH) are the hepatic manifestations of the metabolic syndrome; worrisome is the booming increase in pediatric age. To recreate the full spectrum of juvenile liver pathology and investigate the gender impact, male and female C57Bl/6 mice were fed with high fat diet plus fructose in the drinking water (HFHC) immediately...
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ژورنال
عنوان ژورنال: Clinical Medicine
سال: 2018
ISSN: 1470-2118,1473-4893
DOI: 10.7861/clinmedicine.18-2-s54